Event Details

The optimal concentration of oxygen to initiate respiratory support of preterm infants at birth is still a highly controversial topic, yet critical to optimising infant care. In the 1990s, 100% oxygen was abandoned and replaced with 21% oxygen, then later increased to 30% oxygen. However, given limited research, the most effective level for resuscitation of preterm newborns is still uncertain. 

The TORPIDO 30/60 Randomised Clinical Trial, conducted across six countries, aimed to seek some clarity around the optimality of oxygen levels in order to improve safety and quality of care in the NICU. Newborns were randomly assigned to a 30% or 60% oxygen condition, and outcomes focused on death and brain injury at 36 weeks.

The study found no significant differences in primary outcomes of death and brain injury between groups. Dr Oei will discuss the study, explore its implications on future practice and research, and emphasise the continued need to answer this fundamental question. 

For more details, access the study here: 
https://jamanetwork.com/journals/jama/article-abstract/2842699?guestAccessKey=84b29dbd-1874-40de-9279-6683a513eaa1&utm_source=linkedin_company&utm_medium=social_jama&utm_term=18987464884&utm_campaign=article_alert&linkId=886639178